|
KMID : 0376419780020000123
|
|
Chonbuk University Medical Journal
1978 Volume.2 No. 0 p.123 ~ p.130
|
|
|
Study for Effect of Super High Intensity of Sound on Cochlear Hair Cells of Guinea Pig at Fixed Frequency
|
|
|
|
|
Abstract
|
|
|
To know the extending area and cegree of damage of the cochlear hair cells involved by super high intensity of sound, 12 guinea pigs were exposed to very high intensity of pure tone with frequency of 4900 Hz at 130 dB S.P.L. and 100 dB S.P.L..
12 guinea pigs were devided into 4 groups ;
Group A, was exposed to pulsating sound of 130 dB S.P.L. for 8 hours.
Group A, was exposed to continuous sound of 130 dB S.P.L. for 4 hours.
Group Bl was exposed to pulsating sound of 100 dB S.P.L. for 8 hours.
Group B, was exposed to continuous sound of 100 dB S.P.L. for 4 hours.
The duration and the interval of pulsating sound were 1 sec.. Fortyeight hours later the animals were sacrificed and each cochlear hair cells was observed with phase contrast microscope and electron microscope. The results were as follows ;
1) The morphological changes of the involved area of the cochlear hair cells exposed to super high intensity of pure tone were same degree in Group Al and Alf and in Group Bl and B2.
2) The extent of changes in the hair cells involved by the higher intensity was wider than those involved by the lower intensity.
3) The hair cells of central portion of the involved region were more severely damaged than those of marginal portions.
4) The 3rd row of outer hair cells was more severe in the morphological changes than the other two. The inner hair cells showed relatively normal appearance or mild change.
5) The electron microscopical findings of the fine structures of the involved outer hair cells were relatively severe degenerative clianges in the cytoplasm and cuticular plate but mild changes in the nucleus and mitochondria.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|